Advantage Red Dogs 22-55lbs (10-25kg) - 4 Pack

This product can be use safely for puppies older than 8 weeks.

hi, The main differences are Advantage kills only fleas within one hour, targeting adult and larvae stages, where as Advantix kills fleas generally within five minutes targeting all stages of the flea's life cycle i.e. adult larvae and egg. It also kills ticks and mosquitoes. I hope this helps.